Matthias Liechti

Matthias Emanuel Liechti is the research group leader at the Liechti Lab at the University of Basel.


Matthias Liechti is a professor for clinical pharmacology and internal medicine the University Hospital Basel. With his psychopharmacology research group at the Departments of Biomedicine and Clinical Research, Matthias Liechti investigates the pharmacology of psychoactive substances both in vitro and in humans.

The group is best known for the work on the acute effects of MDMA (ecstasy) and LSD in humans. In experimental clinical studies, Matthias Liechti described the acute effects of MDMA, LSD, and psychostimulants in healthy subjects. The team also conducts Pharmaco-fMRI studies in collaboration with the Department of Psychiatry and conducts clinical trials using LSD in patients.

His Liechti Lab works closely together with MindMed.

He sits on the advisory board of the MIND Foundation.

Notable Research Papers

  • Gender differences in the subjective effects of MDMA (Liechti et al., 2001)
  • Acute psychological effects of 3, 4-methylenedioxymethamphetamine (MDMA,“Ecstasy”) are attenuated by the serotonin uptake inhibitor citalopram (Liechti et al., 2000)
  • Psychological and cardiovascular effects and short-term sequelae of MDMA (“ecstasy”) in MDMA-naıve healthy volunteers (Vollenweider et al., 1998)

Find more on Google Scholar or PubMed

In our database you will also find him as an author on many more papers.

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