Music as an Intervention to Improve Hemodynamic Tolerability of Ketamine in Depression

The purpose of this study is to assess the impact of music on patients receiving a course of intravenous (IV) ketamine for treatment-resistant depression (TRD), both unipolar and bipolar. The primary outcome measures changes in systolic blood pressure throughout each 40-minute infusion. Secondary outcomes include repeated measures of mood, anxiety, suicidality, and psychological/physical pain. Aspects of the treatment experience, with and without music, will also be explored.

Topic Music Bipolar Disorder Treatment-Resistant Depression Depression Pain
Compound Ketamine Placebo
Country Canada
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Trial Details



Trial Number

Sponsors & Collaborators

Douglas Mental Health University Institute
This company doesn't have a full profile yet, it is linked to a clinical trial.

Measures Used

Montgomery-Asberg Depression Rating Scale
A ten-item diagnostic questionnaire used to measure the severity of depressive symptoms in patients with mood disorders.

Data attribution

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