MDMA, Cortisol and Memory

This interventional trial (n=60) investigates the impact of MDMA on memory and cortisol levels in ecstasy users.

Led by Kim Kuypers at Maastricht University, it employs a double-blind, placebo-controlled, crossover design with four treatment conditions. Novice and heavy ecstasy users will be compared, assessing memory performance and neuroendocrine reactions under various conditions.

The study aims to understand the role of cortisol in MDMA-induced memory impairment and how this may vary between genders. Recruitment is ongoing, with anticipated enrolment of 60 participants starting from November 2008.

Topic Healthy Subjects
Compound MDMA Placebo
Country Netherlands
Visit trial
Status Unknown status
Results Published No
Start date 01 November 2008
End date 01 January 2012
Phase Not Applicable
Design Blinded
Type Interventional
Generation First
Participants 60
Sex All
Age 18- 99
Therapy No

Trial Details

This interventional trial, led by K.P.C. Kuypers at Universiteit Maastricht, investigates MDMA's impact on memory and cortisol levels in ecstasy users. Employing a double-blind, placebo-controlled, crossover design with four treatment conditions, the study compares novice and heavy ecstasy users to understand MDMA's effects on memory and neuroendocrine reactions, especially the role of cortisol and gender differences. Recruiting began in November 2008, aiming to enrol 60 participants.

NCT Number NL24590.068.08

Sponsors & Collaborators

Maastricht University
Maastricht University is host to the psychopharmacology department (Psychopharmacology in Maastricht) where various researchers are investigating the effects of psychedelics.

Data attribution

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