Ketamine and Postoperative Depressive Symptom-PASSION

Perioperative depression symptom (PDS) is one of the common mental comorbidity, and influences the clinical outcomes and prognosis. However, there is no rapid acting treatment to deal with it during the limited hospital stay.

This study aims to determine whether ketamine could improve the depressive symptom of peirioperative patients. It will also examine the safety for administrating ketamine as an antidepressant intraoperatively.

Meanwhile, it will show if ketamine could improve anxiety, postoperative pain or delirium. This trial also will bring great concerns on patients with perioperative mental health and explore the measures to improve their psycho-related prognosis.

Topic Depression
Compound Ketamine
Country China
Visit trial
Status Completed
Results Published No
Start date 05 June 2017
End date 20 November 2018
Phase Phase II
Design Open
Type Interventional
Generation First
Participants 84
Sex All
Age 18- 99
Therapy No

Trial Details

Perioperative depression symptom (PDS) is one of the common mental comorbidity, and influences the clinical outcomes and prognosis. However, there is no rapid acting treatment to deal with it during the limited hospital stay. This study aims to determine whether ketamine could improve the depressive symptom of peirioperative patients. It will also examine the safety for administrating ketamine as an antidepressant intraoperatively. Meanwhile, it will show if ketamine could improve anxiety, postoperative pain or delirium. This trial also will bring great concerns on patients with perioperative mental health and explore the measures to improve their psycho-related prognosis.

Trial Number NCT03086148

Sponsors & Collaborators

Beijing TianTan Hospital
This company doesn't have a full profile yet, it is linked to a clinical trial.

Data attribution

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