Effects of MDMA on memory when witnessing or committing a simulated crime

This trial (n=60) investigated the effect of MDMA (75mg) on the formation of memories. This was tested by simulating a crime (virtual reality). The trial found no significant effect of heightened vulnerability to external suggestions from MDMA.

Topic Healthy Subjects
Compound MDMA
Country Netherlands
Visit trial
Status Completed
Results Published Yes
Start date 12 September 2018
End date 30 May 2022
Chance of happening 100%
Phase Phase I
Design Blinded
Type Interventional
Generation First
Participants 60
Sex All
Age 18- 40
Therapy No

Trial Details



NCT Number NTR7665

Sponsors & Collaborators

Maastricht University
Maastricht University is host to the psychopharmacology department (Psychopharmacology in Maastricht) where various researchers are investigating the effects of psychedelics.

Papers

Remembering Molly: Immediate and delayed false memory formation after acute MDMA exposure
This trial (n=60) examined the delayed effects of MDMA (75 mg) on false memory in 60 healthy participants using a basic, associative word list (Deese/Roediger-McDermott (DRM)) paradigm and two applied misinformation tasks using a virtual reality crime, which were administered immediately after the MDMA session and one week later (sober). MDMA increased false memory for related but non-critical lures during the immediate test and decreased false memory for critical lures after a delay. Overall, findings suggest there is no heightened vulnerability to external suggestion in response to MDMA intoxication.

Data attribution

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