Effects of alcohol (0.5 %0) and MDMA (100 mg) on (simulated) driving performance, driving related performance and traffic safety

This crossover study (n=20) aimed to assess the effects of a single dose of MDMA (100 mg) and/or alcohol (0.5%) on simulated driving performance.

Conducted by Rijksuniversiteit Groningen, it was part of the EU project DRUID to combat impaired driving. Subjects, aged between 21 and 40, were given various combinations of substances in a controlled experimental design.

The study, approved by the Medical Ethics Committee, started in April 2010 and enrolled 20 participants. It involved driving tests conducted post-drug intake and psychomotor tests afterwards.

The primary outcome was driving performance, with secondary outcomes including analyses of drug levels and questionnaire results. Contacts for the study were provided for both public and scientific inquiries.

The results of this trial can be found here.

Topic Healthy Subjects Safety
Compound MDMA
Country Netherlands
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Trial Details



Trial Number

Sponsors & Collaborators

University of Groningen
The University of Groningen, established in 1614, is a prestigious institution that ranks among the world's top universities. It has taken a pioneering role in the interdisciplinary research of psychedelics, harnessing its rich academic heritage and a forward-looking approach to exploring the potential of psychedelic substances in treating various mental health conditions.

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