EEG Characteristics in ECT

The investigators will be examining slow-wave characteristics in depressed patients receiving electroconvulsive therapy (ECT) using direct current electroencephalogram (dcEEG) by anesthesia induction agent.

Topic Healthy Subjects
Compound Placebo Ketamine
Country United States of America
Visit trial
Status Unknown status
Results Published
Start date 01 October 2019
End date 01 October 2020
Chance of happening 0%
Phase Phase I
Design Blinded
Type Interventional
Generation First
Participants 26
Sex All
Age 18- 65
Therapy No

Trial Details

This is a pilot project using dcEEG to look at infra-slow waves in depressed patients receiving ECT randomized to ketamine or methohexital where ketamine suppresses infra-slow waves. The rationale for this project is to identify biomarkers of treatment adequacy in ECT, which could lead to decreased morbidity and mortality with the procedure and lessen the burden of depression in our patient population.

NCT Number NCT04022226

Sponsors & Collaborators

University of Ottawa
The University of Ottawa launched  The Psychedelics & Spirituality Studies Initiative (PSSI) in 2021. PSSI is an interdisciplinary group of faculty and graduate students who share a common interest in the study of psychedelics, spirituality and integrative healing.

McGill University
Psychedelic research is well underway at McGill University. At the Neurobiological Psychiatry Unit, researchers are assessing the effects of psychedelics at the behavioral, brain circuit, neuronal, and subcellular levels.

Queen's University
This company doesn't have a full profile yet, it is linked to a clinical trial.

Data attribution

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