Classic psychedelics, health behavior, and physical health

This survey study (n=613) found that lifetime classic psychedelic use was modestly associated with more healthy tobacco-related and diet-related behaviours and a healthier BMI. Greater psychological insight was also modestly associated with health behaviour, diet- & exercise-related improvements.

Abstract

Background: Preliminary evidence suggests that classic psychedelics may be effective in the treatment of some psychiatric disorders, yet little remains known about their effects on health behavior and physical health.

Objectives: The purpose of this study was to investigate associations of lifetime classic psychedelic use and psychological insight during one’s most insightful classic psychedelic experience with health behavior and physical health.

Methods: Using data representative of the US population with regard to sex, age, and ethnicity (N=2822), this study examined associations of lifetime classic psychedelic use and psychological insight with health behavior and physical health.

Results: Lifetime classic psychedelic use was associated with more healthy tobacco-related and diet-related behavior (β=0.05 and 0.09, respectively). Among lifetime classic psychedelic users (n=613), greater Psychological Insight Questionnaire (PIQ) total scale, PIQ Avoidance and Maladaptive Patterns (AMP) subscale, and PIQ Goals and Adaptive Patterns (GAP) subscale scores were each associated with higher odds of more healthy exercise-related behavior [adjusted odds ratios (aOR) (95% confidence interval, CI=1.38 (1.13–1.68), 1.38 (1.13– 1.68), and 1.32 (1.10–1.60), respectively] and higher odds of having a healthy body mass index (BMI) [aOR (95% CI)=1.32 (1.07–1.63), 1.36 (1.10–1.69), and 1.23 (1.01–1.50), respectively], and greater GAP subscale scores were associated with more healthy diet-related behavior (β=0.10). All PIQ scales were positively associated with some health behavior improvements (overall, diet, exercise) attributed to respondents’ most insightful classic psychedelic experience (β=0.42, 0.18, and 0.17; β=0.40, 0.19, and 0.17; and β=0.40, 0.15, and 0.15, respectively), but only PIQ total scale and AMP subscale scores were positively associated with alcohol-related health behavior improvements (β=0.13 and 0.16, respectively).

Conclusion: Although these results cannot demonstrate causality, they suggest that psychological insight during a classic psychedelic experience may lead to positive health behavior change and better physical health in some domains, in particular in those related to weight management.

Authors: Otto Simonsson, Peter S. Hendricks, Richard Chambers, Walter Osika & Simon B. Goldberg

Summary of Classic psychedelics, health behavior, and physical health

Recent research has found links between classic psychedelic use and better physical health, including lower odds of being overweight or obese and lower odds of having heart disease, diabetes, and hypertension.

In a clinical trial, many participants reported spontaneous health behaviour changes following the administration of psilocybin. If classic psychedelic use can facilitate health behaviour change, it would be important to understand the underlying psychological mechanisms.

Two self-report measures of psychological insight have been used in research on classic psychedelics. The Psychological Insight Questionnaire (PIQ) and the Psychological Insight Scale were used to investigate the associations between lifetime classic psychedelic use and psychological insight during respondents’ most insightful classic psychedelic experience and health behaviour.

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Study details

Topics studied
Population Surveys

Study characteristics
Survey

Participants
2822 Humans

Authors

Authors associated with this publication with profiles on Blossom

Otto Simonsson
Otto Simonsson is a Postdoctoral Research Fellow at the Karolinska Institute where he conducts research on meditation and psychedelics. Otto held a similar position at The Centre for Healthy Minds at the University of Wisconsin-Madison.

Peter Hendricks
Peter Hendricks is a Professor in the Department of Health Behaviour at the University of Alabama. Hendricks's area of expertise lies in substance abuse treatment and prevention.

Institutes

Institutes associated with this publication

Karolinska Institutet
KI is Sweden’s single largest centre of medical academic research which as expanded into the field of psychdelics.

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