Psychedelic-assisted Group Program for First Responders

This interventional feasibility study (n=32) will evaluate the impact of oral psilocybin (10mg) combined with a 12-week group-based programme tailored for firefighters.

Conducted by Empower Research Inc. and the Centre for Neurology Studies in Canada, this study aims to assess the feasibility and effectiveness of integrating psilocybin into a mental health programme designed for first responders. The programme includes weekly sessions on topics such as breathwork, mindfulness, and self-compassion, with Group 1 receiving the standard programme and Group 2 receiving psilocybin in Week 10.

Participants will be assessed at baseline, mid-program, end of program, and six months later. This study started in January 2025 and is expected to conclude by September 2025.

Trial Details

This study is a two-group feasibility study of oral psilocybin combined with a 12-week group-based program, customized for firefighters. Trained facilitators will help create a trauma-informed space for the group (n = 6-8) to thrive and promote cognitive resilience. The topics covered throughout the 12 weeks include breath-work, mindfulness, self-compassion, embodiment, and Internal Family Systems work.

Trial Number NCT06471959

Data attribution

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