Ketamine for Mood Disorders With Suicidal Ideation

This study will explore whether the use of a medication, ketamine, can help patients who come to the ER with thoughts of suicide by improving their mood and reducing thoughts of suicide.

Ketamine has been used for this purpose in patients who have been hospitalized, but it has not been well studied in the ER. The investigators are first trying to show that patients and doctors in the ER find the treatment acceptable.

The investigators also hope to determine whether ketamine is effective in decreasing the severity of patient’s suicidal thinking while in the ER. If this treatment works, future studies will look at whether it can help patients be discharged from the hospital earlier.

Topic Depression Suicidality
Compound Ketamine
Country United States of America
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Trial Details



Trial Number

Sponsors & Collaborators

The Miriam Hospital
This company doesn't have a full profile yet, it is linked to a clinical trial.

Papers

A feasibility study of low-dose ketamine for acute management of suicidal ideation
This open-label study (n=14) finds that ketamine (35mg/70kg) infusion significantly reduced suicidal ideation (SI) in patients in the emergency department (ED). The acceptability (willingness to try treatment) was also high (>70%) among patients and physicians. The study is the first to test this in the ED.

Data attribution

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