An Evaluation of Psilocybin’s Effect on Cardiac Repolarization

This double-blind placebo-controlled trial (n=36) investigates the effects of psilocybin on heart health (Cardiac Repolarization), the dosing includes one (not defined) extra high dose of psilocybin (supratherapeutic).

Topic Safety
Compound Psilocybin
Country United States of America
Visit trial
Status Active, not recruiting
Results Published No
Start date 22 June 2022
End date 01 June 2023
Phase Phase II
Design Blinded
Type Interventional
Generation First
Participants 36
Sex All
Age 18- 65
Therapy No

Trial Details

This study will be a double-blind, single-dose, randomized, placebo-controlled, 4-treatment, 4-period, 12-sequence crossover design in 36 healthy volunteers (adult male and/or female subjects). Subjects will be randomly assigned to 1 of 12 different treatment administration sequences, whereby each sequence will include 3 double-blind treatments (therapeutic dose of psilocybin, supratherapeutic dose of psilocybin, and placebo) and 1 open-label positive control treatment (moxifloxacin).

Trial Number NCT05478278

Sponsors & Collaborators

Usona Institute
The Usona Institute was founded by Bill Linton and Malynn Utzinger. Currently, 18 people are associated with it. The institute is a non-profit that sponsors psilocybin research (and is funded by sponsors/philanthropists).

Data attribution

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