Ketamine Co-induction for Patients With Major Depressive Disorder

Ketamine hydrochloride, an anesthetic medication, has been demonstrated to acutely and rapidly improve depressive symptoms but not yet been adequately studied for this effect when used as part of a general anesthetic for surgery.

This proposed single-centre, double-blinded, randomized clinical trial of adult patients with depression presenting for gynecologic surgery would compare severity of depressive symptoms between patients receiving and not receiving ketamine as part of their general anesthetic.

Topic Depression
Compound Placebo Ketamine
Country Canada
Visit trial
Status Unknown status
Results Published
Start date 12 January 2018
End date 12 January 2019
Phase Phase IV
Design Blinded
Type Interventional
Generation First
Participants 50
Sex Female
Age 18- 65
Therapy No

Trial Details

Ketamine hydrochloride, an anesthetic medication, has been demonstrated to acutely and rapidly improve depressive symptoms but not yet been adequately studied for this effect when used as part of a general anesthetic for surgery. This proposed single-centre, double-blinded, randomized clinical trial of adult patients with depression presenting for gynecologic surgery would compare severity of depressive symptoms between patients receiving and not receiving ketamine as part of their general anesthetic.

Trial Number NCT03666494

Sponsors & Collaborators

University of Saskatchewan
The University of Saskatchewan is a research-intensive, medical doctoral university in Canada which famously hosted Humphrey Osmond in the 1950s.

Saskatoon Health Region
This company doesn't have a full profile yet, it is linked to a clinical trial.

Royal University Hospital Foundation
This company doesn't have a full profile yet, it is linked to a clinical trial.

Data attribution

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