Ketamine-assisted Psychotherapy for Adolescent PTSD (KAP)

This interventional trial (n=5) investigates the safety and feasibility of ketamine-assisted psychotherapy in adolescents with posttraumatic stress disorder (PTSD).

Conducted by the University of Wisconsin, Madison, the study aims to enrol adolescents aged 15-17 who meet DSM-5 criteria for current PTSD. Participants will receive three intravenous ketamine administrations immediately prior to psychotherapy sessions over six weeks, followed by integration sessions and at-home sleep recordings.

The primary objective is to characterise the safety and adverse events associated with ketamine administration, while secondary objectives include assessing recruitment feasibility and exploring the impact on PTSD symptom severity.

Recruitment is expected to begin in August 2024, with an estimated completion date of August 2025.

Topic PTSD Adolescence and Psychedelics Safety
Compound Ketamine
Country United States of America
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Trial Details



Trial Number

Sponsors & Collaborators

University of Wisconsin-Madison
The Transdisciplinary Center for Research in Psychoactive Substances (TCRPS) was launched at the University of Wisconsin-Madison in 2021.

Data attribution

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