Ketamine and Motivational Enhancement Therapy for the Treatment of Tobacco Use Disorder

This pilot study (n=8) aims to assess the feasibility of using ketamine-assisted treatment for tobacco use disorder, alongside brief motivational enhancement therapy.

Conducted by the Medical University of South Carolina, participants aged 21 to 65, who are daily cigarette smokers with multiple unsuccessful quit attempts, will receive weekly ketamine sessions for three weeks.

The primary outcome will be the feasibility of completing the full treatment. Secondary outcomes include measuring smoking cessation and reduction in cigarettes smoked per day using saliva cotinine levels and self-reported timeline follow-back, respectively. Recruitment for the study is ongoing, with an estimated completion date of May 2024.

Topic Smoking Addiction
Compound Ketamine Placebo
Country United States of America
Visit trial

Trial Details



Trial Number

Sponsors & Collaborators

Medical University of South Carolina
The Medical University of South Carolina (MUSC) partnered with MAPS to create a psychedelic research centre to study the therapeutic effects of psychedelic drugs on mental illness.

Data attribution

A large set of the trials in our database are sourced from ClinicalTrials.gov (CTG). We have modified these post to display the information in a more clear format or to correct spelling mistakes. Our database in actively updated and may show a different status (e.g. completed) if we have knowledge of this update (e.g. a published paper on the study) which isn't reflected yet on CTG. If a trial is not sourced from CTG, this is indicated on this page and you can follow the link to the alternative source of information.