Effect of Stimulant Drugs on Social Perception

The study will improve our understanding of the “prosocial” effects of MDMA, relative to a prototypical stimulant, methamphetamine (MA). The investigators seek to characterize the “uniquely social” effects of MDMA.

Topic Healthy Subjects
Compound Placebo MDMA
Country United States of America
Visit trial

Trial Details



Trial Number

Sponsors & Collaborators

University of Chicago
Research with psychedelics is taking place at the Human Behavioral Pharmacology Lab at the University of Chicago.

National Institute on Drug Abuse
This company doesn't have a full profile yet, it is linked to a clinical trial.

Papers

MDMA enhances positive affective responses to social feedback
This double-blind, placebo-controlled crossover trial (n=36) investigates the effects of two doses of MDMA (52.5-105mg/70kg) compared to both placebo and methamphetamine (20 mg) on responses to personalized social feedback in healthy adults. The study concludes that the higher dose of MDMA increases positive affective responses to social feedback, suggesting a potential mechanism by which MDMA may enhance social connection.

Effects of MDMA on attention to positive social cues and pleasantness of affective touch
This randomized, double-blind, placebo-controlled study (n=36) investigated the effects of MDMA (52.5 to 105 mg/kg) and methamphetamine (20 mg) in healthy young adults on behavioral and psychophysiological response to socially relevant, “affective” touch, and visual attention to emotional faces. The tests showed that MDMA positively influenced responses to affective touch, but neither drug influenced ratings of observed touch.

Data attribution

A large set of the trials in our database are sourced from ClinicalTrials.gov (CTG). We have modified these post to display the information in a more clear format or to correct spelling mistakes. Our database in actively updated and may show a different status (e.g. completed) if we have knowledge of this update (e.g. a published paper on the study) which isn't reflected yet on CTG. If a trial is not sourced from CTG, this is indicated on this page and you can follow the link to the alternative source of information.