Effects of MDMA and Methylphenidate on Social Cognition

The purpose of this study is to assess and compare the effects of a single dose of 3,4-methylenedioxymethamphetamine (MDMA) and methylphenidate (MPH) on emotional and social cognition in healthy subjects.

The investigators hypothesize that MDMA enhances affective perception for positive and impairs perception for negative emotional stimuli compared to placebo or MPH.

Topic Healthy Subjects
Compound Placebo MDMA
Country Switzerland
Visit trial
Status Completed
Results Published
Start date 08 January 2012
End date 04 January 2013
Chance of happening 100%
Phase Phase I
Design Blinded
Type Interventional
Generation First
Participants 30
Sex All
Age 18- 45
Therapy No

Trial Details

The purpose of this study is to assess and compare the effects of a single dose of 3,4-methylenedioxymethamphetamine (MDMA)and methylphenidate (MPH) on emotional and social cognition in healthy subjects. The investigators hypothesize that MDMA enhances affective perception for positive and impairs perception for negative emotional stimuli compared to placebo or MPH.

NCT Number NCT01616407

Sponsors & Collaborators

University of Basel
The University of Basel Department of Biomedicine hosts the Liechti Lab research group, headed by Matthias Liechti.

Data attribution

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