The Effect of LSD on Neural Synchrony, Prosocial Behavior, and Relationship Quality

This double-blind, placebo-controlled crossover trial (n=60) investigates the effects of LSD (50µg) on neural synchrony, prosocial behaviour, and relationship quality in healthy romantic couples.

The study, conducted by Maastricht University, aims to explore whether LSD enhances neural synchrony between partners and if it influences prosocial behaviours. The researchers hypothesize that psychedelics increase prosocial behaviours by increasing neural synchrony.

The trial involves 30 couples receiving both placebo and an oral dose of 50 µg of LSD in a randomized sequence, with a minimum 14-day washout between conditions. The study duration is minimally four weeks, with the primary completion estimated by January 2024.

Topic Healthy Subjects
Compound LSD
Country Netherlands
Visit trial
Status Recruiting
Results Published No
Start date 01 January 2023
End date 01 January 2024
Phase Phase I Phase II
Design Blinded
Type Interventional
Generation First
Participants 60
Sex All
Age 18- 35
Therapy No

Trial Details

The goal of this study is to assess the effects of LSD on neural synchrony, prosocial behavior, and relationship quality in healthy romantic couples.

NCT Number NCT05670184

Sponsors & Collaborators

Maastricht University
Maastricht University is host to the psychopharmacology department (Psychopharmacology in Maastricht) where various researchers are investigating the effects of psychedelics.

Data attribution

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