Study to Assess the Effects of Intranasal Ketamine Along With rTMS for Patients With Treatment-resistant Major Depressive Disorder (TRD)

An open label study to assess the safety, tolerability, and effects of intranasal ketamine in combination with rTMS for patients with treatment-resistant major depressive disorder (TRD). Patients will be given a dose of ketamine followed by 6 weeks of rTMS treatment.

Topic Depression
Compound Ketamine
Country United States of America
Visit trial
Status Not yet recruiting
Results Published
Start date 05 January 2020
End date 05 January 2022
Chance of happening 90%
Phase Phase IV
Design Open
Type Interventional
Generation First
Participants 20
Sex All
Age 18- 65
Therapy No

Trial Details

Investigate the effects of pretreatment using a single, sub-anesthetic dose of intranasal ketamine on the response to a standard course of rTMS in patients who meet the definition of TRD.

NCT Number NCT04352621

Sponsors & Collaborators

University of Cincinnati
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Measures Used

Quick Inventory of Depressive Symptomatology
The Quick Inventory of Depressive Symptomatology (Self-Report) (QIDS-SR16) is a self-report tool designed to screen for depression and measure changes in the severity of symptoms.

Data attribution

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