Study of Ketamine for Depression in Cancer Patients Receiving Palliative Care

This is a phase 2 study of the drug ketamine for the treatment of depression in cancer patients receiving palliative care.

The purpose of this study is to see how useful the drug is at decreasing the severity of depression these patients. Ketamine will be given through the nose.

Topic Depression
Compound Ketamine
Country Canada
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Trial Details



Trial Number

Sponsors & Collaborators

University Health Network Toronto
University Health Network is a public research and teaching hospital network in Toronto. The Nikean Psychedelic Psychotherapy Research Centre was established in 2021.

Papers

A Phase II, Open-Label Clinical Trial of Intranasal Ketamine for Depression in Patients with Cancer Receiving Palliative Care (INKeD-PC Study)
This open-label study (n=20) finds that ketamine (intranasal, 3x, 50-150mg) reduced depression in patients with cancer who were receiving palliative care. On day eight (one day after the last dose), the response and remission rates were 70% and 45%, respectively. The effects were partially sustained in the second week.

Data attribution

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