Single-dose Ketamine for the Reduction of Pain and Depression in the Emergency Department

In this proposal, the investigators will determine if a single dose of intravenous (IV) ketamine (in combination with midazolam) reduces pain severity, depressive symptoms and need for opiate analgesics both in the ED and in the acute recovery period after ED discharge. The investigators will compare the ketamine arm to an active placebo-controlled arm (with midazolam).

Topic Depression Pain
Compound Placebo Ketamine
Country United States of America
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University of Pittsburgh
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