Psilocybin-facilitated Treatment for Chronic Pain

The primary purpose of this study is to preliminarily estimate the efficacy of psilocybin-facilitated treatment for fibromyalgia.

Investigators will assess the impact of psilocybin-facilitated treatment on pain, fatigue, and other fibromyalgia symptoms, in addition to the level of functioning and quality of life.

Investigators will also evaluate potential mediators of treatment (e.g., treatment expectations, pain characteristics, personality, beliefs/cognitions, emotions). Investigators hypothesize psilocybin treatment will significantly reduce symptom severity in fibromyalgia patients.

Topic Fibromyalgia Pain
Compound Placebo Psilocybin
Country United States of America
Visit trial
Status Not yet recruiting
Results Published
Start date 01 January 2022
End date 01 July 2024
Chance of happening 88%
Phase Phase II
Design Blinded
Type Interventional
Generation First
Participants 30
Sex Female
Age 25- 65
Therapy No

Trial Details

The primary purpose of this study is to preliminarily estimate the efficacy of psilocybin-facilitated treatment for fibromyalgia. Investigators will assess the impact of psilocybin-facilitated treatment on pain, fatigue, and other fibromyalgia symptoms, in addition to the level of functioning and quality of life. Investigators will also evaluate potential mediators of treatment (e.g., treatment expectations, pain characteristics, personality, beliefs/cognitions, emotions). Investigators hypothesize psilocybin treatment will significantly reduce symptom severity in fibromyalgia patients.

NCT Number NCT05068791

Sponsors & Collaborators

University of Alabama
Researchers at the University of Alabama are investigating the potential use of psychedelics in a number of disorders.

Data attribution

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