Optimizing Microdosing and Meditation (OMM)

This randomised controlled trial (n=24) will investigate the feasibility of combining meditation with psilocybin microdosing in healthy adults, comparing a group receiving only psilocybin microdoses to a group receiving both psilocybin microdoses and meditation training.

The study, conducted by the National University of Natural Medicine in Portland, Oregon, aims to assess recruitment, retention, acceptability, safety and tolerability of this combined intervention. All participants will receive psilocybin microdoses twice weekly for two weeks, with half randomly selected to also participate in weekday morning online meditation sessions.

The researchers will collect data on sleep quality, heart rate variability and other biometrics using Oura rings, as well as quality of life scores and qualitative feedback. This trial takes advantage of Oregon’s legal psilocybin services programme to study these interventions in a real-world context.

The researchers hypothesise that if the model proves feasible, it could potentially lead to a safe, effective and low-cost intervention combining group meditation with psilocybin microdosing for mental health challenges like depression.

Topic Microdosing
Compound Psilocybin
Country United States of America
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