Evaluating the Feasibility, Safety and Efficacy of Psychotherapy Assisted Psilocybin for Treatment of Severe OCD

The purpose of the current study is to explore new alternative options for the treatment of OCD that can widely and continuously benefit patients.

Specifically, the aim of this study is to investigate the feasibility, safety and efficacy of psilocybin-assisted psychotherapy for treatment of severe OCD. 

Topic Obsessive-Compulsive Disorder
Compound Psilocybin
Country Israel
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Trial Details



Trial Number

Sponsors & Collaborators

Beersheva Mental Health Center
This company doesn't have a full profile yet, it is linked to a clinical trial.

Measures Used

Yale-Brown Obsessive Compulsive Scale
The Yale Brown Obsessive-Compulsive Scale (Y-BOSC) is considered the gold-standard to assess OCD severity. The scale consists of ten items and measures the severity and type of symptoms in people with OCD over the previous seven days. The scale is used at initial diagnosis as well as during follow up sessions after treatment. The scores range from 0 to 4, with higher scores indicating greater symptoms of OCD severity.

Beck Depression Inventory
The Beck Depression Inventory (BDI) contains 21 self-report items, completed using a multiple-choice format. Scores range from 0-63 with higher scores associated with more severe depression.

5-Dimensional Altered States of Consciousness Questionnaire
The 5D-ASC scale measures altered states of consciousness and contains 94 items (visual analog scales).

Obsessive Compulsive Inventory-Revised
The OCI-R is an 18-item self-report questionnaire based on the earlier 84-item OCI. Participants rate the degree to which they are bothered or distressed by specific OCD symptoms in the past month.

Data attribution

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