Effect of the Addition of Ketamine to Sevoflurane Anesthesia in Electroconvulsive Therapy

The investigators evaluate the effects of a subanesthetic dose of ketamine, administered as an adjunct to sevoflurane, on duration of seizure activity, hemodynamic profile and recovery times during electroconvulsive therapy (ECT) in patients with major depression.

Topic Depression
Compound Placebo Ketamine
Country Turkey
Visit trial
Status Unknown status
Results Published
Start date 01 July 2014
End date 01 October 2014
Chance of happening 0%
Phase Phase IV
Design Blinded
Type Interventional
Generation First
Participants 60
Sex All
Age 18- 70
Therapy No

Trial Details

Patients will randomly allocate, to either a sevoflurane-ketamine (Group SK), sevoflurane-saline (Group SS) receiving group. Mean arterial pressure (MAP) and heart rate (HR) will record prior to anesthetic induction (T1); following anesthetic induction (T2); and 0, 1, 3, and 10 min after the seizure has ended (T3, T4, T5, and T6, respectively). Motor and EEG seizure durations will be recorded.

NCT Number NCT02267980

Sponsors & Collaborators

Inonu University
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Data attribution

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