Prosocial Effects of MDMA (PEM)

This early Phase I crossover trial (n=34) investigates the effects of familiarity on the prosocial effects of MDMA (100mg) in social interactions. The study aims to test the hypothesis that MDMA produces greater prosocial effects when administered in the presence of a familiar person compared to an unfamiliar one.

MDMA has shown promise in treating PTSD when combined with psychotherapy, with the patient-therapist relationship considered crucial. The study involves four sessions where participants receive MDMA (100mg) or a placebo, engaging in a 15-minute conversation with either a familiar or unfamiliar person. The trial commenced on July 21, 2023, and is estimated to be completed by June 2024. Hanna Molla can be contacted for study-related information.

Topic PTSD
Compound MDMA Placebo
Country United States of America
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Trial Details



Trial Number

Sponsors & Collaborators

University of Chicago
Research with psychedelics is taking place at the Human Behavioral Pharmacology Lab at the University of Chicago.

Data attribution

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