Role Of Ketamine in Treatment-Resistant Major Depressive Disorder And Its Effect on Suicidality

In this study we will assess the effect of Ketamine infusion on depressive symptoms and in particular its effect on Suicidal behavior, ideation and thoughts in patients with treatment- resistant MDD.

Topic Treatment-Resistant Depression Suicidality Depression
Compound Ketamine
Country Egypt
Visit trial
Status Not yet recruiting
Results Published No
Start date 12 January 2019
End date 02 January 2021
Phase Phase I
Design Open
Type Interventional
Generation First
Participants 30
Sex All
Age 18- 99
Therapy No

Trial Details

A Twice repetition of IV infusion of 0.5 mg/kg of ketamine produces an antidepressant response in individuals with treatment-resistant MDD The work aims to: 1. To assess the onset of action and degree of improvement and the duration of antidepressant effect of ketamine in a sample of patients with treatment -resistant major depressive disorder. 2. To find out whether the onset of Ketamine antidepressant effect is associated with an improvement of suicidality in those patients.

Trial Number A Twice repetition of IV infusion of 0.5 mg/kg of ketamine produces an antidepressant response in individuals with treatment-resistant MDD The work aims to: To assess the onset of action and degree of improvement and the duration of antidepressant effect of ketamine in a sample of patients with treatment -resistant major depressive disorder. To find out whether the onset of Ketamine antidepressant effect is associated with an improvement of suicidality in those patients.

Sponsors & Collaborators

Assiut University
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Data attribution

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