Effects and Therapeutic Potential of Psilocybin in Alcohol Dependence

This trial is an open-label pilot study (N = 10) designed to assess the effects of psilocybin in alcohol dependent participants, demonstrate the feasibility of the integrated behavioral/pharmacologic intervention, and provide preliminary outcome and safety data.

Topic Addiction Alcohol Use Disorder
Compound Psilocybin
Country Canada
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Trial Details



Trial Number

Sponsors & Collaborators

University of Ottawa
The University of Ottawa launched  The Psychedelics & Spirituality Studies Initiative (PSSI) in 2021. PSSI is an interdisciplinary group of faculty and graduate students who share a common interest in the study of psychedelics, spirituality and integrative healing.

Canadian Institutes of Health Research
This company doesn't have a full profile yet, it is linked to a clinical trial.

Papers

The psychedelic debriefing in alcohol dependence treatment: illustrating key change phenomena through qualitative content analysis of clinical sessions
This open-label pilot study (n=10) of psilocybin-assisted treatment of alcohol dependence (21mg/70kg) presents a qualitative content analysis of the 17 debriefing sessions conducted in the pilot study, which occurred the day after corresponding psilocybin medication sessions. Participants articulated a series of key phenomena related to change in drinking outcomes and acute subjective effects of psilocybin.

Psilocybin-assisted treatment for alcohol dependence: a proof-of-concept study
This open-label study (n=10) combined therapy with two psilocybin (21-28mg) sessions and showed a significant reduction in (heavy) drinking days up to 36 weeks later.

Data attribution

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