The Effects of Low Dose Ketamine on Cardiovascular Function

This terminated interventional trial (n=6) aimed to investigate the effects of low-dose ketamine on cardiovascular function.

Conducted by the University of Texas Southwestern Medical Center, the study focused on understanding how ketamine affects sympathetic nervous system activity and cardiovascular function, particularly in adults.

The trial, which commenced in November 2020 and concluded in May 2021, enrolled non-obese participants meeting specific blood pressure criteria. The primary objective was to measure muscle sympathetic nerve activity burst frequency using microneurography, while secondary outcomes included arterial blood pressure and blood vessel diameter.

The study employed a crossover design, with participants randomly assigned to receive either low-dose ketamine or a saline placebo. However, the trial was terminated as the laboratory shifted focus due to changes in extramural funding.

Compound Ketamine Placebo
Country United States of America
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University of Texas
The University of Texas is conducting research with psychedelics across locations in Houston, Austin, Dallas and San Antonio.

Data attribution

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