A Single Ketamine Infusion Combined With Music for Suicidal Ideation

This open-label trial (n=200) investigates the efficacy of a single ketamine infusion combined with music for suicidal ideation (SI) during a depressive episode.

It’s conducted by The University of Texas Health Science Center at Tyler and aims to address the shortcomings of current treatments for suicidal ideation associated with major and bipolar depression.

Participants, aged 18-64, with a DSM-IV diagnosis of depressive episode and positive suicidal ideation, are included. Exclusion criteria involve active psychotic symptoms, current manic episode, and various medical conditions.

The trial compares the effects of ketamine alone, ketamine with music, music alone, and treatment as usual. The primary outcome measure is the Scale for Suicidal Ideation (SSI), with secondary outcomes including depression scores and quality of life measures. Recruitment started in July 2021, with a projected completion date of April 2023.

Topic Suicidality Depression
Compound Ketamine
Country United States of America
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Trial Details



Trial Number

Sponsors & Collaborators

The University of Texas Health Science Center
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