Conscious Dying/Conscious Living: Ketamine-Assisted Psychotherapy

This randomised, double-blind, placebo-controlled trial (n=120) will investigate the effects of Ketamine-Assisted Psychotherapy (KAP) on patients with terminal illnesses.

Administered by The Ketamine Research Foundation, the study will take place at five locations and involve 18 subjects at each site. Participants will undergo two separate intramuscular ketamine sessions accompanied by psychotherapeutic support over 4-6 weeks.

Assessments will measure changes in anxiety levels and distress related to death and dying. A naturalistic comparator group will also undergo assessments and have the option for crossover KAP treatment.

The primary outcome measures are changes in the State-Trait Anxiety Inventory (trait assessment only) and the Death and Dying Distress Scale. The study aims to evaluate the efficacy of KAP in palliative and hospice care settings.

Trial Details



Trial Number

Data attribution

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