This open-label trial (n=20) investigates if psilocybin (25mg, 2x) and Visual Healing (an ‘optimised’ set and setting using VR with a nature theme) will be significantly better in treating those with alcohol use disorder than a ‘standard’ set and setting.
Both groups will get one session without Visual Healing and have the option of choosing this in the second session. The difference between the groups is the “chance to view nature-themed videos before and after the psychedelic sessions.“
Compound Psilocybin
Country United States of America
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Sponsors & Collaborators
John Wayne Cancer InstituteThis company doesn't have a full profile yet, it is linked to a clinical trial.
Papers
Nature-themed video intervention may improve cardiovascular safety of psilocybin-assisted therapy for alcohol use disorderThis open-label pilot study (n=20) investigated the use of Visual Healing, a nature-themed video intervention, to enhance set and setting in psychedelic-assisted therapy with psilocybin for alcohol use disorder (AUD). Participants were randomized to either use Visual Healing or standard procedures during two psilocybin dosing sessions. The study found that Visual Healing was feasible, safe, and well-tolerated, with participants viewing the videos without adverse events. It also noted a significant decrease in alcohol use in both groups and found that Visual Healing did not interfere with the psychedelic experience or treatment outcomes related to alcohol use. The study suggests that Visual Healing may reduce cardiovascular risks in psychedelic therapy and calls for further research to replicate these findings and explore set and setting interventions with other psychedelic medications and indications.