American Psychiatrists’ Opinions About Classic Hallucinogens and Their Potential Therapeutic Applications: A 7-Year Follow-Up Survey

This survey (n=131) conducted among American psychiatrists aimed to assess their opinions about psychedelics & PAT in 2023, comparing the results with a similar study conducted in 2016. The findings revealed a significant positive shift in attitudes among American psychiatrists since 2016, with a majority expressing moderate to strong belief in the therapeutic potential of psychedelics for treating psychiatric conditions (81%) and substance use disorders (61%).

Abstract of American Psychiatrists’ Opinions About Classic Hallucinogens and Their Potential Therapeutic Applications: A 7-Year Follow-Up Survey

Background: Psilocybin, a classic hallucinogen, may eventually be approved by the United States Food and Drug Administration for treatment-resistant depression. However, we are aware of only one published national survey of American psychiatrists regarding their opinions about hallucinogens and hallucinogen-assisted therapy, conducted by our group in 2016. Here, we report a repeat survey, using virtually identical methods, assessing whether American psychiatrists display greater optimism about the therapeutic use of hallucinogens in 2022–23.

Methods: We e-mailed our survey instrument to 1,000 randomly selected American Psychiatric Association members—250 resident-fellows and 750 attending psychiatrists—in late 2022 and early 2023. We calculated descriptive statistics and used a non-parametric trend test to compare the current survey responses with those from 2016. We also constructed a multivariate logistic regression model to assess attributes of respondents that predicted moderate/strong agreement with plans to incorporate hallucinogen-assisted therapy into their own practice.

Results: The response rate was 13.1% (N = 131). Respondents were demographically similar to the 2016 respondents. A majority moderately/strongly believed that hallucinogens show promise in treating psychiatric conditions (80.9%) and substance use disorders (SUDs) (60.8%). Large majorities also moderately/strongly supported research into hallucinogens’ therapeutic potential for psychiatric conditions (93.9%) and SUDs (88.6%), as well as federal funding of associated clinical trials (84.7% and 80.9%, respectively). Comparisons to 2016 showed significantly increased optimism regarding the therapeutic promise of hallucinogens and decreased concern about risks, with 50.4% of respondents reporting moderate/strong intentions to incorporate hallucinogen-assisted therapy into their practice.

Conclusions: Our data reveal a striking positive shift in attitudes toward the therapeutic potential of hallucinogens among American psychiatrists since 2016, with a majority of responding psychiatrists planning to incorporate hallucinogen-assisted therapy into their practice if regulatory approval is granted.”

Authors: Brian S. Barnett, Miranda Arakelian, David Beebe, Jared Ontko, Connor Riegal, Willie O. Siu, Jeremy Weleff & Harrison G. Pope

Summary of American Psychiatrists’ Opinions About Classic Hallucinogens and Their Potential Therapeutic Applications: A 7-Year Follow-Up Survey

Classic hallucinogens such as psilocybin, LSD, and mescaline exert their psychoactive effects via 5-HT2A receptor agonism. Despite accelerating research into therapeutic applications, data are limited on American psychiatrists’ current attitudes regarding these drugs.

In 2016, 65% of American psychiatrists moderately/strongly agreed that classic hallucinogens increase the risk for subsequent psychiatric disorders, and 48% moderately/strongly agreed that classic hallucinogens increase the risk for long-term cognitive impairment. Fewer than half agreed that classic hallucinogens show promise in treating psychiatric disorders.

The authors conducted a repeat national survey of American psychiatrists’ opinions about classic hallucinogens, and hypothesized that respondents would be more optimistic about their therapeutic potential and less concerned about their risks.

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American Psychiatrists' Opinions About Classic Hallucinogens and Their Potential Therapeutic Applications: A 7-Year Follow-Up Survey

https://doi.org/10.1089/psymed.2023.0036

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Cite this paper (APA)

Barnett, B. S., Arakelian, M., Beebe, D., Ontko, J., Riegal, C., Siu, W. O., ... & Pope, H. G. (2023). American Psychiatrists' Opinions About Classic Hallucinogens and Their Potential Therapeutic Applications: A 7-Year Follow-Up Survey. Psychedelic Medicine.

Study details

Topics studied
Population Surveys

Study characteristics
Longitudinal Survey

Participants
121 Humans