Psychedelics feature in Forbes yet again. This time Bruce Y. Lee takes a look at the results of the recent trial “increased global integration in the brain after psilocybin therapy for depression.”
Category Popular Press
Published in Forbes
Paper Featured
Increased global integration in the brain after psilocybin therapy for depressionThis fMRI study assessed the impact of psilocybin on brain function in two clinical trials of depression. In both trials, the antidepressant response to psilocybin was rapid and sustained, correlating with decreases in fMRI brain network modularity. Network cartography analyses indicated that serotonin (5-HT) 2A receptor-rich higher-order functional networks became more functionally interconnected and flexible after a psilocybin treatment. Together, the findings from both studies point to global increases in brain network integration as an antidepressant mechanism in psilocybin therapy.