Study to Assess the Effects of Intranasal Ketamine Along With rTMS for Patients With Treatment-resistant Major Depressive Disorder (TRD)

An open label study to assess the safety, tolerability, and effects of intranasal ketamine in combination with rTMS for patients with treatment-resistant major depressive disorder (TRD). Patients will be given a dose of ketamine followed by 6 weeks of rTMS treatment.

Topic Depression

Compound Ketamine

Country United States of America

Visit trial

Status Not yet recruiting

Results Published

Start date 05 January 2020

End date 05 January 2022

Chance of happening 90%

Phase Phase IV

Design Open

Type Interventional

Generation First

Participants 20

Sex All

Age 18- 65

Therapy No

Trial Details

Investigate the effects of pretreatment using a single, sub-anesthetic dose of intranasal ketamine on the response to a standard course of rTMS in patients who meet the definition of TRD.

NCT Number NCT04352621

Sponsors & Collaborators

University of Cincinnati
This company doesn't have a full profile yet, it is linked to a clinical trial.

Measures Used

Quick Inventory of Depressive Symptomatology
The Quick Inventory of Depressive Symptomatology (Self-Report) (QIDS-SR16) is a self-report tool designed to screen for depression and measure changes in the severity of symptoms.

Data attribution

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