Psychedelic-Assisted Psychotherapy: A Paradigm Shift in Psychiatric Research and Development

This theoretical commentary (2018) highlights the paradigm-shifting implications of psychedelic-assisted psychotherapy in light of a triple crisis within contemporary psychiatry, concerning the lack of reliable therapeutics, a heterogeneity of diagnoses, and a reductionist understanding of mental disorders that explains away the psyche by reducing it to underlying brain processes, whereas the new paradigm aims to incorporate these dimensions in a holistic understanding of human beings and the social factors of their culture and environment.

Abstract

“Mental disorders are rising while development of novel psychiatric medications is declining. This stall in innovation has also been linked with intense debates on the current diagnostics and explanations for mental disorders, together constituting a paradigmatic crisis. A radical innovation is psychedelic-assisted psychotherapy (PAP): professionally supervised use of ketamine, MDMA, psilocybin, LSD and ibogaine as part of elaborated psychotherapy programs. Clinical results so far have shown safety and efficacy, even for “treatment resistant” conditions, and thus deserve increasing attention from medical, psychological and psychiatric professionals. But more than novel treatments, the PAP model also has important consequences for the diagnostics and explanation axis of the psychiatric crisis, challenging the discrete nosological entities and advancing novel explanations for mental disorders and their treatment, in a model considerate of social and cultural factors, including adversities, trauma, and the therapeutic potential of some non-ordinary states of consciousness.”

Author: Eduardo E. Schenberg

Summary of Psychedelic-Assisted Psychotherapy: A Paradigm Shift in Psychiatric Research and Development

Introduction

Psychedelic substances are currently being tested in clinical studies for the treatment of neuroses, alcoholism, end-of-life anxiety, and chronic pain. However, a portion of patients do not seem to benefit from psychedelic-assisted therapies or end up relapsing.

Several authors hypothesized that psychedelics may have therapeutic effects due to their neuroplasticity and environmental sensitivity. This means that psychedelics may open a window of flexibility for patients to modify rigid behaviors, thought patterns, and emotional reactions.

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