Inside the Dispute Over a High-Profile Psychedelic Study

The latest article from Shayla Love at Vice gives us an insight into a very public dispute on the methods and claims made in this recent study by some prolific psychedelic scientists.

Category Popular Press
Published in Vice

People Featured

Shayla Love
Shayla Love is a senior staff writer at Vice.

Paper Featured

Increased global integration in the brain after psilocybin therapy for depression
This fMRI study assessed the impact of psilocybin on brain function in two clinical trials of depression. In both trials, the antidepressant response to psilocybin was rapid and sustained, correlating with decreases in fMRI brain network modularity. Network cartography analyses indicated that serotonin (5-HT) 2A receptor-rich higher-order functional networks became more functionally interconnected and flexible after a psilocybin treatment. Together, the findings from both studies point to global increases in brain network integration as an antidepressant mechanism in psilocybin therapy.